Monday, March 7, 2011

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Dexamethasone and asthma

Studies showed that a 2-day course of dexamethasone is as effective as a 5-day course of prednisolone in the treatment of mild to moderate asthma. Both drugs have the same bioavailability (fraction of an administered dose of unchanged drug that reaches the systemic circulation) but the half life of prednisolone varies between 8-24 hr while that of dexamethasone ranges between 32-72 hr.

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