Tuesday, June 14, 2011

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Iron deficiency anemia - Microcytic hypochromic cells

It is a typical peripheral blood smear for an iron deficiency anemia patient showing microcytic hypochromic red blood cells at magnification 50X.
In normal conditions, the size (diameter) of an RBC should roughly correspond to that of the nucleus of a lymphocyte. In this slide, it is smaller.
The numerous small dots refer to platelets and they are found in a larger number (thrombocytosis), a finding commonly seen in iron deficiency anemia.
Differential diagnosis includes:
1) anemia of chronic disorders,
2) thalassemia,
3) sideroblastic anemia.


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