Saturday, May 15, 2010

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Beginning of the pancreas

The pancreas develops from the fore gut as ventral and dorsal buds. Since it is a fore gut structure, pain associated with acute pancreatitis is mostly localised to the epigastrium. Both buds have their own drainage duct. During development of the fore gut, there is rotation and fusion of the 2 buds to surround the superior mesenteric vessels.
The larger dorsal pancreas forms the adult body, tail and upper part of the head while the ventral bud forms the rest of the head and the uncinate process.
Fusion of the duct system results in the duct of the ventral bud to become the main duct a/k/a duct of Wirsung. This duct shares an opening with the common bile duct at the major papilla a/k/a ampulla of Vater to drain into the duodenum. The duct of the dorsal bud persists as a smaller accessory duct of Santorini which drains through the minor papilla.

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